The Risks and Benefits of Anti-Diabetic Drugs

Glimepiride is an oral hypoglycemic drug for the treatment of type 2 diabetes. However, you should talk to your doctor first before taking this drug as it is associated with an increasing number of cardiovascular mortality.

Glimepiride can be a potent anti-diabetic drug. This sulfonylurea drug is marketed as Glista OD by Cadila Pharmaceuticals Ltd. and Amaryl by Sanofi-Aventis. The drug works by lowering your blood glucose level by stimulating your pancreas to produce more insulin as well as boosting the intracellular insulin receptor activity.


Type 2 diabetes is a medical condition in which your body has a high amount of blood sugar because of its failure to use insulin normally. Your doctor will prescribe diet, exercise and Glimepiride to stimulate your pancreas to induce it to make more insulin as well as make your body highly sensitive to insulin. You can use Glimepiride without or with insulin.


A tablet of Glimepiride is taken once a day, usually with a big, hearty meal. It is highly recommended that you follow prescription label directions or your doctor’s instructions. If you missed a dose, take it the soonest unless you are nearing the time for the next dose, then you can skip it and continue with your regular medication schedule.

Hypoglycemia and Hyperglycemia:

Taking Glimepiride may result to low or high blood sugar level-hypoglycemia or hyperglycemia. It is important that you know the symptoms of hypoglycemia and hyperglycemia and what to do if you experience them.

If you have low blood sugar or hypoglycemia, your doctor may tell you to check your blood sugar, drink or eat beverage or food that contains sugar such as fruit juice or candy or get a medical care. Some symptoms of hypoglycemia are:

· Shakiness

· Sweating

· Lightheadedness or dizziness

· Pale skin

· Jerky or clumsy movements

· Headache

· Tingling or numbness around the mouth

· Irritability or nervousness

· Weakness

· Hunger

Non-treatment of hypoglycemia may result to seizures, confusion or loss of consciousness. On the other hand, you would know if you have high blood sugar or hyperglycemia, if you experience:

· Extreme thirst

· Extreme hunger

· Blurred vision

· Weakness

· Frequent urination

Hyperglycemia, if not treated, may lead to diabetic ketoacidosis which is a life-threatening condition. Call your doctor immediately if you experience decreased consciousness, vomiting and nausea, dry mouth and shortness of breath.

Read more about Glimepiride in the newly review posted.